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Therapeutic antibodies use a range of mechanisms that directly or indirectly kill the cancer cells

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To overcome this difficulty, a tamoxifen (Tam)inducible Col2a1-driven Cre recombinase (Col2a1 Tam -cre) mice were used along with the Igf1r floxed mice

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Exagamglogene autotemcel (exa-cel [Casgevy, Vertex Pharmaceuticals/CRISPR Therapeutics]) is the first FDA- and EMA-approved gene editing therapy, indicated for treating sickle cell disease and transfusion-dependent beta thalassaemia in patients aged 12 and older