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The millimolar GSH intracellular concentrations, the low plasma micromolar concentrations and the low GSH redox potential ( E 0 = 240 mV) make GSH an ideal and perfect cellular redox buffer (Figure 2) (3237), cell proliferation (3237), and cell apoptosis (3842)

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Changes in actin polymerization status can affect focal adhesion signaling complexes, integrin-mediated signaling, and transcriptional responses that govern cellular movement and structural adaptation