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& Ghorbian, S
In that case, theres little concern that youre overdosing
This metabolic acceleration can temporarily elevate oxidative stressthe imbalance between free radicals and antioxidant defensesparticularly during the first 48 weeks of therapy initiation
This is a reason why mitochondria are a main target for GSH to neutralise ROS and reduce oxidative stress
Figure: Simplified ferroptotic cascade
