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Klunk et al., 1996

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For example, C16-carnitine (10 M) may impair mitochondrial function in rat ventricular myocytes by accelerating ROS production and increasing the probability of mitochondrial permeability transition pore (mPTP) opening, whereas low concentrations (1 and 5 M) of C16-carnitine lightly hyperpolarize the m but do not open the mPTP [293]

Metab Brain Dis 35(4):559578

Although carnitine deficiency has been reported in autism, it is not reported as frequently as this hypothesis might suggest, Beaudet said