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Biochemistry 39, 54745482

Front Microbiol 3:17

Its direct suppression of NF-kB, the master inflammatory transcription factor involved in psoriasis, gives it the strongest mechanistic rationale

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598 FTH1 knockdown in neurons significantly inhibits cell viability and causes mitochondrial dysfunction, while overexpression of FTH1 impairs ferritinophagy, downregulates the expression of LC3 and NCOA4, and finally inhibits cell ferroptosis

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