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In this study, catalase inhibitors were added to bovine catalase solution, ferric chloride solution, cell lysates of control cells and experimentally generated catalase knockdown cells (CAT KD), and these mixtures were reacted with hydrogen peroxide to determine the percentage of hydrogen peroxide remaining in the reaction solution after a certain time

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Acquired drug resistance prevents cancer therapies from achieving stable and complete responses.1 Emerging evidence implicates a key role for nonmutational drug resistance mechanisms underlying the survival of residual cancer persister cells.2-4 ...

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