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DOAJ (DOAJ: Directory Open

HSPs released from tumor cells can bind to surface receptors on antigen presenting cells (APCs) and elicit tumor-specific killers by means of antigen cross-presentation

(PubMed) Das R, Qubty W

[DOI] [PubMed] [Google Scholar] 31.Shouval D

The cytoprotective (reduced reactive oxygen species and reduced cell senescence) effects of ergothioneine on endothelial cells exposed to hyperglycaemic conditions have been shown to be dependent on sirtuin 1 and sirtuin 6 activities and their cellular targets (Reference DOnofrio, Servillo and Giovane89) , which notably include NF- B, the aforementioned transcriptional regulator of SLC22A4 (Reference Maeda, Hirayama and Kobayashi63)

FASN is an enzyme overexpressed in many cancer types that plays a key role in tumorigenesis [50]