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ROS stress in cancer cells and therapeutic implications

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Surprisingly, these anti-inflammatory benefits have recently been attributed to central neuronal GLP-1RAs [171], highlighting the potential use of incretin receptor agonists for neurological diseases with inflammatory components

Hakeshzadeh F, Tabibi H, Ahmadinejad M, et al

The link of ASCT2 with this pathology was systematically postulated in 2005 when an eminent review pointed out that this protein supplies cancer cells with glutamine to satisfy specific metabolic and signaling needs (Fuchs and Bode, dealing with this protein

Figure 4: Serum IGF-1 levels in different experimental groups In addition to changes in serum levels, both KID and KIR mice saw significant increases in body weight from 4 to 16 weeks in age