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Studies published in Cell Metabolism and Nature Communications document its effects on AMPK activation, insulin sensitivity, exercise performance, and metabolic aging in animal models and early human studies

Regardless of these caveats, there seems to be sufficient evidence to warrant investigation of a potential clinical role for radioprotective agents

For instance, insulin resistance may reduce autophagic activity, thereby impacting the cells response to energy and nutritional status [84]

Wolkenberg and Sur 2010)

For a 75kg (165lb) person, this suggests 2.25 to 3.75mg daily, aligning with the 10 to 20 unit range at 20mg/mL concentration