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We hypothesize that inhibition of the Munc13-4STX7 interaction by ENDOs should recapitulate the impaired endosomal maturation phenotype observed in Munc13-4 deficiency, manifested as an enlarged endolysosomal compartment

& Clemens, J

Immunity 48:10061013

[Crossref] Poljsak B, Suput D, Milisav I (2013) Achieving the balance between ros and antioxidants: when to use the synthetic antioxidants

Preclinical research often shows the powerful effects of resveratrol, particularly in decreasing ALT and TG levels, although clinical trials have not consistently validated these findings (86)

3.5 Removal of GST affinity tag after protease cleavage in solution If the protein was digested in solution, the target protein can be purified further by re-chromatography on the glutathione Sepharose column to remove any un-cleaved fusion protein and the GST moiety