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SAMe metabolism disruption reduced cell growth and induced apoptosis [219]

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Ichim, T

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Several measures of Parkinsons disease symptoms improved significantly, and when the investigators increased the dosage of thiamine into the second month of treatment, the benefits became even more pronounced

As a result, -tocopherol with three methyl groups is the most active of the tocopherols and -tocopherol with one methyl group is the least active (Ungurianu et al., 2021)
