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Journal of Biological Chemistry, 278 (7), 4981-4987
Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling
They are generated in the presence of oxygen by abstraction of hydrogen and addition of radicals to double bonds
In 2023, Peace et al
This results in downstream increases in insulin-like growth factor-1 (IGF-1), a key mediator of growth and metabolic regulation
Abstract Disturbances of mitochondrial function and oxidative stress are considered to be the molecular basis of the origin and development of various diseases, including mitochondrial diseases
