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With traditional treatments focusing primarily on symptom management, there is a growing emphasis on disease-modifying therapies targeting the underlying causes of dementia, such as amyloid-beta plaques and tau protein tangles

Analysis of CSF biomarkers revealed that IL-6 and GFAP levels increased from baseline to post-treatment, coinciding with a trending decrease in cytokines and chemokines associated with senescence

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However, only a few of them, including TNF- inhibitors, IL-1 inhibitors, TGF-1, GDF-6 and resveratrol, are effective in alleviating discogenic pain

For mechanistic comparison with cytoprotective and migration-modulating peptides, see our Copper peptides & tissue repair guide

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