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, Impact of long COVID on health-related quality-of-life: An OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT)

found that cardiac microvascular endothelial cells isolated from T2DM mice exhibited increased expression of pro-ferroptotic genes (Tfrc, Acsl4, Ptgs2), decreased expression of anti-ferroptotic genes (Gpx4, Slc7a11), and elevated lipid peroxidation (MDA, 4-HNE), indicating that hyperglycemia also induces ferroptosis in endothelial cells [97]

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Furthermore, other research indicates that ferroptosis in EESCs promotes the production of vascular endothelial growth factor A (VEGFA) and interleukin-8 (IL8)

Additionally, Kai et al

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