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Ann Clin Med Case Rep 2025

More detailly, aripiprazole induced an increase in Firmicutes phyla, Peptostreptococcaceae, Clostridiaceae and Ruminococcaceae family and in multiple minor genera such as Clostridium sensu stricto 1, Ruminiclostridium 5, Intestinibacter, Eubacterium coprostanoligens, Peptoclostridium, Eubacterium oxidoreducens, Christensenellaceae uncultured and Clostridia Family XIII, with a decrease in the relative abundance of Ruminococcus 1

For instance, cascade multienzyme nanoparticles (e.g., PtMnIr) can deplete GSH, continuously generate ROS, and release damage-associated molecular patterns (DAMPs) to promote dendritic cell maturation and cytotoxic T lymphocyte infiltration [161]

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If it was exposed to heat during shipping or storage, or if it is well past its expiration date, the lyophilized powder may have undergone chemical changes that prevent proper dissolution

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