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This finding emphasizes the importance of maintaining mitochondrial protein synthesis capacity to prevent metabolic disorders

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In the current study, we directly compared the performance of adult and aged xCT +/+ and xCT / mice in the Barnes maze task, using a protocol with longer inter-trial intervals to avoid bias due to differences in spatial working memory, to specifically assess the effect of xCT deletion on age-related changes in hippocampus-dependent reference memory

doi: 10.1016/j.pharmthera.2021.107996

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