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Thus, the ability to measure nearly all eicosanoids and related species should become increasingly focused on their collective bioactivity rather than as distinct species working in isolation

For example, agents such as verapamil or cyclosporine, which reverse multidrug resistance caused by P-glycoprotein in dilute tissue culture, may lose their effect as the cell concentration in tissue culture increases (Tunggal et al, 1999)

In a mouse limb bud culture system, acrolein induced impairment of limb bud differentiation, indicative of a teratogenic action (Stahlmann et al., 1985)

or Have intolerable adverse effects associated with allopurinol treatment requiring treatment discontinuation and have trialled probenecid at doses up to 2 g per day or to a maximum tolerated dose

But it's I have a guy that Weidman hooked me up with

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