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Moreover, a recent meta-analysis concluded that melatonin treatment significantly increases the CPR but not LBR in ART cycles

Liang X, Yan Z, Ma W, Qian Y, Zou X, Cui Y, et al

doi: 10.4236/ijcm.2018.99055

Schlegel PN, Sigman M, Collura B, De Jonge CJ, Eisenberg ML, Lamb DJ, et al
The L-Carnitine-supplemented group showed consistent results, reporting an increase in sperm motility, sperm concentration, and sperm acrosin activity

Albeit transcriptionally quiescent, sperm are indicated to involve non-coding (ncRNA) and coding (mRNA)