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This study demonstrated that mRNA carried in near-neutral-charge LPXs administered intravenously can effectively target, transfect and activate dendritic cells systemically, providing strong vaccine priming in preclinical mouse models, and reported early phase I vaccination data in cancer patients
Selcuk, Z
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Malignant transformation of oral lichen planus and oral lichenoid lesions: a meta-analysis of 20095 patient data
The cell density was normalized to an OD 600 of 0.2, loaded with 2 m DiSC 3 (5) dye, and incubated for 20 min in the dark for probe fluorescence to stabilize
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