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One of the most successful applications of biological conditions is conditional reprogramming (CR), which involves co-culturing primary cells with irradiated mouse 3T3-J2 fibroblasts in the presence of RHO-related protein kinase (ROCK) inhibitor Y-27632 [135]
Symptoms may include severe wheezing, coughing, chest tightness, and shortness of breath, much like asthma
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