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thrombophilia, a high baseline hematocrit, or use of prothrombotic medications), fasting could become detrimental

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Studies have demonstrated that chronic administration of AOD-9604 leads to adaptive changes in adipose tissue, including increased expression of beta-3 adrenergic receptors and enhanced sensitivity to lipolytic signals

It is also advised to avoid mega doses of pyridoxine in pregnant or breastfeeding patients unless necessary, since safety data for doses beyond the recommended dietary allowance are limited

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