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Lin, M., Rajfer, J., Swerdloff, R

The system was initially neutralized and solvated in a 150 mM KCl environment using a CHARMM-GUI web server 65,66

It is essential to recognize that the enzymes employed for polysaccharide degradation may be inhibited by oversulfated GAGs, preventing the breakdown of those that contain an excess of sulfate residues or exhibit unusual sulfation patterns

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Any future trial should also inform our understanding of the relationship between QoL and costs collecting resource use and cost data to allow estimation of the resource impact of any changes in QoL