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10.1002/mas.1280120102

One common inquiry that arises for those prescribed isotretinoinmore popularly known by its brand name, Accutaneis whether it is safe to take Vitamin C in conjunction with this potent acne medication

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Another study evaluating the impact of exercise on oxidative stress markers in male Wistar rats revealed notable increases in creatinine and urea levels, superoxide generation, antioxidant enzymes (catalase and superoxide dismutase), and oxidative damage in CKD groups compared to sham-treated animals [133]

The reactions are documented in animal models and reported anecdotally in human users

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