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Collectively these data indicate that CHAC1 supports Fe-S protein function under cysteine starvation through an enhanced association with the mitochondria

Next, we performed a cytokine array to gain more insight into the immune landscape in the tumor microenvironment following the combined administration of sertraline and RT (Supplementary Fig

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Additionally, ferroptosis inhibitors like Fer-1 and pioglitazone have been shown to reverse AKI damage in a mouse model by targeting ferroptosis, offering promising avenues for AKI treatment (Hosohata et al., 2022)

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