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Introducing impurities, heavy metals, or degradation byproducts into a research subject can cause inflammationthe exact opposite of what you are trying to achieve
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This cross-sectional study, however, is limited by a small sample size and the inability to confirm causality between SCFA depletion and gut barrier impairment

"Vitamin B12 in Health and Disease"

P., Dizikes, L

Further research is ongoing, but NNMT remains a high-interest target in metabolic science