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Several lines of evidence have shown the replication of SARS-CoV-2 in human enterocytes and its detection in stool samples as well as an altered intestinal microbiota composition in patients with COVID-19, which correlate with disease severity and inflammatory biomarkers [290]

It is triggered by the GTPases mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2), located in the OMM

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