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From the initial oncology diagnosis, more than half of patients who received anthracycline therapy manifested with cardiac abnormalities after 1020 years later ( 2 , epirubicin 600 mg/m 2 ) or the use of low-dose anthracyclines (doxorubicin 250 mg/m 2 and epirubicin 600 mg/m 2 ) accompanied with smoking, hypertension, diabetes, obesity, age over 60 years old, and/or other risk factors ( For survivors with previous anthracycline therapy, the asymptomatic stage is usually characterized by left ventricular (LV) wall thinning, LV diameter increase, and subsequent LV wall stress increase, which is similar to dilated cardiomyopathy ( 2 ( 2 , respectively