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Institutional Review Board Statement This research was approved by the local Ethic Committee (case number 380-59-10106-17-100/290) and by the Directorate of Veterinary (UP/I-322-01/15-01/22)

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Gene expression analysis with RTqPCR Gene expression was analyzed via reverse transcriptase quantitative polymerase chain reaction (RTqPCR) using TaqMan probes (Life Technologies) or SSO Universal Probes Master Mix (Bio-Rad)

Here's how it compares to other commonly used compounds: GHK-Cu Matrixyl (Pal-KTTKS) Epithalon GHK-Cu Matrixyl (Pal-KTTKS) Epithalon GHK-Cu's key differentiator is the depth of its gene expression modulation it doesn't just stimulate one target (like collagen) but appears to reset aging gene expression patterns across thousands of genes