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Vincent A, Lahr BD, Wolfe F, et al

Reconstitute AOD 9604 by adding sterile bacteriostatic water to the lyophilized powder, usually using 1-2 ml depending on vial size

The reason for this strong correlation is that in general, p K a increases linearly with a G (g) ( r 2 0.70.95), as one would expect: higher a G (g) means a stronger HA bond, thus a weaker acid

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Thus, while permanent FOXO4 inhibition is inapplicable, the fact that as a CPP it can block a specific protein-protein interaction make FOXO4-DRI selective, and thereby well-tolerated and effective