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Neuro-imaging research found a direct causal link between B12 status, damage to the brain and consequent memory impairment

Energy & metabolism Red blood cells & anemia B12 is essential to red blood cell formation

Systematic review and meta-analysis of randomized placebo-controlled trials of folate and vitamin B12 for depression

At the molecular level, reduced NNMT activity shifts cellular methylation patterns, potentially altering epigenetic modifications via changes in SAM/S-adenosylhomocysteine (SAH) ratios

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