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It also requires careful medical supervision and involves substantial cost

Therefore, we propose that this modification more likely promotes the release of NHR-49 from chromosomal DNA via electrostatic repulsion

Article Information Published Online: May 28, 2024

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The protein can also cause apoptosis (cellular suicide), and in senescent cells, FOXO4 communicates with p53 to prevent this

This increased oxidative stress contributes to hepatocyte apoptosis and triggers inflammatory responses that promote fibrogenesis in MASLD
