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Antimicrobial use, human gut microbiota and Clostridium difficile colonization and infection

The lancet

Chronic inflammation can hinder the hair growth cycle, causing thinning and hair loss

Similarly, the class I HDAC inhibitor SAHA, but not a class II HDAC inhibitor, increases the expression of PGC-1 thus leading to enhanced mitochondrial biogenesis, oxygen consumption in adipose tissue and skeletal muscle from mice with type 2 diabetes (174)

Notably, the enzyme has been linked to obesity and type 2 diabetes (T2D)

doi: 10.1016/j.stemcr.2015.04.008
