glutathione and alcho Detox: The Science of Glutathione Alcohol – Thomas DeLauer Glutathione, Alcohol and drugs

Acknowledgments We would like to thank for the support of Sub-project of Academician Zhong Shizhen Workstation, Joint cultivation project of Southwest Medical UniversityThe Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University (Osteopathy of Integrated Traditional Chinese and Western Medicine), and Innovation team project of The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University

Phytochelatins (-(EC) n -glycine) are polymerized forms of 2 to 11 GSH molecules, produced by phytochelatin synthase (PCS), a -EC transpeptidase (Figure 1: Chelation)

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Iron metabolism critically intersects with oxidative stress pathways, as iron overload potentiates reactive oxygen species production via Fenton chemistry, which transforms H 2 O 2 into highly destructive hydroxyl radicals (OH) (77, 147, 148)

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