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It is thus a primary cellular tool in order to maintain steady state concentrations of ascorbic acid (a perfect AO) in accelerated oxidation conditions.[112] It acts as a coenzyme with liver enzyme glutathione-insulin transhydrolase which helps in the catabolism and degradation of the protein hormone inulin.[9] Targeting endogenous NO, intracellular glutathione, conjugates with NO to form an S-nitrosoglutathione (GSNO) adduct that in-turn is cleaved by the thioredoxin system to produce glutathione and NO

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10.3390/cells8040379 Cells 275 YanS.TuZ.LiuZ.FanN.YangH.YangS.et al (2018)

doi: 10.1038/s41467-022-32552-1

Tsukamoto et al., 2018)