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Further to this, data from naturally aged, healthy wild-type mice provides supporting evidence by also showing an inverse relationship between serum B12 and IL- 6

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It is believed to influence hypothalamic and neuroendocrine pathways involved in sleep and stress regulation
Long-term studies in mice show that Epithalon administration significantly extended maximum lifespan by 12.3% and increased the lifespan of the last 10% of survivors by 13.3% compared to control groups, while showing no adverse effects on body weight or food consumption