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A likely possibility is that the low glutamate content of the caudate and the putamen in HD results from chronic failure of the normal reuptake mechanism for glutamate released at synapses, with or without any excessive rate of release of this neurotransmitter

[DOI] [PubMed] [Google Scholar] 22.Sun Y., Pu L.Y., Lu L., Wang X.H., Zhang F., Rao J.H

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The biopsy findings typically show megaloblastic erythropoiesis with hyperplastic and dysplastic changes