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This is not a pharmacokinetic effect but rather a physiological one

The electron transfer from NADH+ and FADH+ to NAD and FAD by complexes 1 and 4 produce O 2 radicals which are then converted into H 2 O 2 enzymatically by the catalytic activity of SOD

In the case of CAP, the inflammatory response frequently leads in an excess of ROS, aggravating lung damage and compromising pulmonary function

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TP53 Deficient/Mutant AMLs Are Resistant to Individual BH3 Mimetics: High Efficacy of Combined Inhibition of Bcl-2 and Mcl-1

C-IV: type IV collagen