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L'utilisation de ce mdicament en cas d'encphalopathie hpatique et d'insuffisance rnale svre ncessite une surveillance mdicale en raison des risques lis au mtabolisme de l'ammoniaque

Transcriptome analyses of cells with acute TCAi showed robust activation of the response to amino acid deprivation

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The survival rate of WT was about 80% whereas that of OE lines was between 40 and 52%, which suggested that RcGPX4 negatively mediated seedlings of transgenic plants in response to freezing treatment (Figure 6)

Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity

In a study by Kraus et al., NNMT inhibition in obese mice not only reduced fat mass but also spared lean muscle mass , suggesting that the compound does not induce general catabolism, a common side effect of many weight-loss agents (Kraus D, 2014)