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Mirogabalin, a gabapentinoid that binds to the 2-subunit of the voltage-gated calcium channel and has significantly higher efficacy, was found to be safe but less effective than PGB and placebo at a dose of 15 mg once or twice daily [19]

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Nitrate-rich fruit and vegetable supplement reduces blood pressure in normotensive healthy young males without significantly altering flow-mediated vasodilation: A randomized, double-blinded, controlled trial

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doi: 10.1093/ndt/gfq738