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This review seeks to synthesize previous experiences and examples to guide developing new diagnostic and therapeutic strategies for CNS diseases, as well as to enhance drug design for more effective delivery across the BBB

doi: 10.2337/db21-0336

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Although not yet FDA-approved, the peptide is expected soon but requires medical supervision and planning to protect muscle mass

Common treatments include vitamin C infusions, B-vitamin complexes, Myers' Cocktail, glutathione, NAD+, and hydration therapy

However, there is concern that increased flux of glutamate to the TCA cycle could lead to decreased glutamate availability for glutathione synthesis