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The areas where their effects overlap are minimal

This accumulation of MMP-9 in mitochondria damages the mitochondrial membrane, triggering apoptotic pathways and contributing to the progression of DR (122, 123)

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10.1038/ncb1123 [DOI] [PubMed] [Google Scholar] 29.Hosaka T, Biggs WH 3rd, Tieu D, Boyer AD, Varki NM, Cavenee WK, Arden KC

Notably, 3.2.6 Treatment of other systemic diseases Myocardial infarction (MI), an acute cardiovascular emergency, is primarily treated by curtailing the progression of myocardial necrosis and promoting functional recovery (Wang et al

While the relevance to humans is debated, the exclusion criteria from clinical trials make this a firm boundary