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In this process, two molecules of GSH are consumed to reduce one molecule of peroxide, yielding GSSG and water (or an alcohol)

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Metabolic abnormalities are one of the hallmarks of pancreatic cancer, and pancreatic cancer cells can adapt to biosynthesis, energy intake, and redox needs through metabolic reprogramming to tolerate nutrient deficiency and hypoxic microenvironments

10.1038/s41467-020-20154-8

Meanwhile, MC1R is an upstream regulator influencing MITF activity [105]