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These symptoms are not only associated with many chronic diseases

doi: 10.1002/micr.30287 32 SerafinDLesesneCBMullenRYGeorgiadeNG
Furthermore, 4-HNE induces mitochondrial dysfunction by binding to mitochondrial proteins, leading to electron leakage and increased ROS production

10.1016/j.phymed.2023.154684 41 FuhrmannD

Inflammation is also triggered after surgery in response to protecting the body from infection or trauma

According to the TCGA database, The expression levels of SLC7A11 mRNA in Cervical cancer (CESC), Cholangiocarcinoma (CHOL), Colonic adenocarcinoma (COAD), Esophagus cancer (ESCA), Head and neck squamous cell carcinoma (HNSC), chromophobe kidney cell carcinoma (KICH), Clear cell carcinoma of kidney (KIRC), Papillary cell carcinoma of the kidney (KIRP), Liver cell carcinoma (LIHC), Lung adenocarcinoma (LUAD), Squamous cell carcinoma of the lung (LUSC), Adenocarcinoma of the pancreas (PAAD), Rectum adenocarcinoma (READ), Sarcoma (SARC), Cutaneous melanoma (SKCM), Stomach adenocarcinoma (STAD), and Endometrial carcinoma of the flesh (UCEC) were significantly higher than those in adjacent normal tissues
