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PubMed Staresinic, M., Sebecic, B., Patrlj, L., Jadrijevic, S., Suknaic, S., Perovic, D., Aralica, G., Zarkovic, N., Borovic, S., Srdjak, M., Hajdar, S., Kopljar, M., Batelja, L., Boban-Blagaic, A., Turcic, I., Amic, F., Ruenzi, E., Rucman, R., Seiwerth, S., & Sikiric, P

Cheap, mass-produced, or pre-mixed formulations sitting on shelves rapidly oxidize and lose potency

For example: deeper slow-wave sleep is linked to growth hormone release, and one study showed DSIP may help stimulate GH release during recovery from sleep deprivation

This integrative role connects it to chronobiology research rather than isolated sleep studies

As a result, HPLC purity is an estimate, not a guarantee