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The same results were attained in a similar trial conducted in 2001.82 In 2005, a 6 month double blind crossover study of aerosol tobramycin was carried out on 30 patients and revealed no change in exacerbation rate, but the number of hospitalizations and duration of hospital stay were reduced during the tobramycin phase.83 In 2005 a smaller uncontrolled study was carried out in which aerosolized tobramycin (300mg, twice daily) was administered to 41 patients with non-CF BE and Pseudomonas infection

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