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In the control group, the pH was neutral in the esophagus, but acidic in the stomach, weakly acidic in both the duodenum and jejunum, and finally neutral in the ileum (Fig

Examples include poly(N-isopropylacrylamide) (PNIPAM)-MSNs with thermo-responsive swelling for on-demand release of drugs and chitosan-MSNs with mucoadhesive character for oral delivery [73,74]

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