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lack of MC ligands): while individuals carrying a mutation in this gene present with fair skin and red hair (202), Pomc - / - mice on a black coat mouse strain (129;B6) are still black, due to the high ligand independent activity of this receptor (203)

J Neurosci 27: 1018510195, 2007

Reaction products from a standard MSA-DH assay were fractionated by preparative HPLC separation (compare Figure 4A) and the malate containing fraction was subjected to enantiomeric separation on a Chirex ligand exchange phase 3126

There are many possible causes of GI bleeding, including hemorrhoids, peptic ulcers, tears or inflammation in the esophagus, diverticulosis and diverticulitis, ulcerative colitis and Crohn's disease, colonic polyps, or cancer in the colon, stomach or esophagus

doi:10.1038/362814a0