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[DOI] [PubMed] [Google Scholar] 187.Drapier J.C., Hibbs J.B

Astragalus polysaccharide (APS) can prevent experimental colitis in mice and ferroptosis in human Caco-2 cells by inhibiting this signaling pathway [155], suggesting that ferroptosis may be regulated by the Nrf2/HO-1 signaling pathway in DSS-induced UC

Any peptide that strongly activates innate immune pathways or promotes interferon production requires careful evaluation in the lupus context

Cai M, Sikong Y, Wang Q, Zhu S, Pang F, Cui X

In traumatic shock models, gut barrier collapse generates proinflammatory mediators that form a second hit through mesenteric lymphatic circulation, exacerbating acute pulmonary injury and precipitating multi-organ dysfunction (Magnotti et al., 1998)
