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FIGURE 6 Oxidative stress and inflammation are considered fundamental mediators of chronic obstructive pulmonary disease (COPD) pathophysiology (Figure 6)

Wabaidur SM, Alothman ZA, Khan MR (2013) A rapid method for the simultaneous determination of l-ascorbic acid and acetylsalicylic acid in aspirin C effervescent tablet by ultra performance liquid chromatographytandem mass spectrometry

On the one hand, this is desired, on the other hand it should take place only in the body cells, not already on the way there

Cermerski et al
When cytokines like IL-6 bind to JAK/STAT3, STAT3 becomes phosphorylated

doi: 10.1016/j.toxlet.2009.05.004
