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These micelles, connected via disulfide bonds, augment the stability of nanoparticles and render the release of SPION-CCPMs dependent on intracellular glutathione (GSH) within macrophage endosomes, ensuring effective iron payload within macrophages [62, 63]

Furthermore, many of the features of Parkinson's disease have a mainly non-dopaminergic basis

Recently, neural activity mediated by NMDA-receptors (NMDAR) has been coupled with transcriptional activation of glutamate-cysteine ligase, a key enzyme in GSH production, leading to a sustained GSH-based protection against an oxidative insult 26